Description
Product Characteristics: The human Timeless protein interacts with both the circadian clock protein cryptochrome 2 and with the cell cycle checkpoint proteins Chk1 and the ATR-ATRIP complex and plays an important role in the DNA damage checkpoint response. Down-regulation of Timeless in human cells seriously compromises replication and intra-S checkpoints, indicating an intimate connection between the circadian cycle and the DNA damage checkpoints that is in part mediated by the Timeless protein. Synonyms: Polyclonal TIMELESS antibody, Anti-TIMELESS antibody, timeless homolog, Drosophila antibody.
Target Information: human homolog is a circadian clock gene